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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.

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In 1864, the first barbiturate (barbituric acid) was synthesized.

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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.

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On average, the stomach produces 2 L of hydrochloric acid per day.

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Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.

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