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Once thought to have neurofibromatosis, Joseph Merrick (also known as "the elephant man") is now, in retrospect, thought by clinical experts to have had Proteus syndrome. This endocrine disease causes continued and abnormal growth of the bones, muscles, skin, and so on and can become completely debilitating with severe deformities occurring anywhere on the body.

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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.

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Barbituric acid, the base material of barbiturates, was first synthesized in 1863 by Adolph von Bayer. His company later went on to synthesize aspirin for the first time, and Bayer aspirin is still a popular brand today.

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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.

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More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.

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