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DNA Methylation

DNA Methylation
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Description: Methylation of cytosine followed by a guanine
Methylation of cytosine followed by a guanine


cytosine O / O—P —O—CH2 guanine II o O I A In the DNA of differentiated cells, a methyl group (red) is most often attached to a cytosine that is fol— lowed by a guanine. H \ NH2 B A model of DNA shows methyl groups (red) attached to a cytosine—guanine pair on complementary DNA strands. When the cytosine on one strand is methylated, enzymes methylate the cytosine on the other strand. This is why a methylation tends to persist in a cell’s descendants.
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