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Symptoms of kidney problems include a loss of appetite, back pain (which may be sudden and intense), chills, abdominal pain, fluid retention, nausea, the urge to urinate, vomiting, and fever.
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Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
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The longest a person has survived after a heart transplant is 24 years.
Divorce Rates, Selected Countries In many countries divorce rates have risen in recent decades.
Selected Neurocognitive Disorders Resulting in Dementia
Selected Human Viral Diseases
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