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In Eastern Europe and Russia, interferon is administered intranasally in varied doses for the common cold and influenza. It is claimed that this treatment can lower the risk of infection by as much as 60–70%.

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As many as 20% of Americans have been infected by the fungus known as Histoplasmosis. While most people are asymptomatic or only have slight symptoms, infection can progress to a rapid and potentially fatal superinfection.

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Cucumber slices relieve headaches by tightening blood vessels, reducing blood flow to the area, and relieving pressure.

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The horizontal fraction bar was introduced by the Arabs.

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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.

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