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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.

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Once thought to have neurofibromatosis, Joseph Merrick (also known as "the elephant man") is now, in retrospect, thought by clinical experts to have had Proteus syndrome. This endocrine disease causes continued and abnormal growth of the bones, muscles, skin, and so on and can become completely debilitating with severe deformities occurring anywhere on the body.

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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.

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Everyone has one nostril that is larger than the other.

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More than 50% of American adults have oral herpes, which is commonly known as "cold sores" or "fever blisters." The herpes virus can be active on the skin surface without showing any signs or causing any symptoms.

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