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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
In 1864, the first barbiturate (barbituric acid) was synthesized.
The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.
People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
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