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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.

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Approximately 500,000 babies are born each year in the United States to teenage mothers.

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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.

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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.

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