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Hippocrates noted that blood separates into four differently colored liquids when removed from the body and examined: a pure red liquid mixed with white liquid material with a yellow-colored froth at the top and a black substance that settles underneath; he named these the four humors (for blood, phlegm, yellow bile, and black bile).

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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.

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For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.

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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.

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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.

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