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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.

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A cataract is a clouding of the eyes' natural lens. As we age, some clouding of the lens may occur. The first sign of a cataract is usually blurry vision. Although glasses and other visual aids may at first help a person with cataracts, surgery may become inevitable. Cataract surgery is very successful in restoring vision, and it is the most frequently performed surgery in the United States.

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In 1864, the first barbiturate (barbituric acid) was synthesized.

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Illicit drug use costs the United States approximately $181 billion every year.

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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.

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