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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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On average, the stomach produces 2 L of hydrochloric acid per day.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.