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Approximately one in four people diagnosed with diabetes will develop foot problems. Of these, about one-third will require lower extremity amputation.

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After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.

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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.

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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.

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According to the National Institute of Environmental Health Sciences, lung disease is the third leading killer in the United States, responsible for one in seven deaths. It is the leading cause of death among infants under the age of one year.

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