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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.

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In 1864, the first barbiturate (barbituric acid) was synthesized.

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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.

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Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.

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There are 60,000 miles of blood vessels in every adult human.

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