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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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Nearly 31 million adults in America have a total cholesterol level that is more than 240 mg per dL.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The FDA recognizes 118 routes of administration.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%