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Description: The five sequential mannosyl transfer reactions from GDP-mannose are catalyzed by separate glycosyltransferase s, as are the four mannosyl transfers from dolichol phosphate mannose. The latter is synthesized in turn from GDP-mannose. The acceptor site on the polypeptide chain is an asparagine residue two positions to the N side of a serine or threonine. The whole process occurs in the endoplasmic reticulum, with translocation to the lumen of the ER occurring after transfer of the fifth mannose residue. Picture Stats: Views: 265 Filesize: 247.66kB Height: 870 Width: 674 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34303 |