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| Description: The subunit is believed to have two states: one open only to the outside (brown one open only to the inside (blue) A dot between two symbols indicates noncovalent binding, a line indicates covalent attachment and (as in phosphorylation). Cardiotonic steroids (e.g., digoxin) inhibit the Na+–K+ pump, resulting in increased Ca2+ ion concentration in heart muscle, which, in turn, leads to stronger contractions of the heart muscle. Picture Stats: Views: 292 Filesize: 213.83kB Height: 526 Width: 554 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34346 |