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Description: This figure depicts the initial unbranched pathway from erythrose-4-phosphate and PEP to chorismic acid. The first reaction is driven by loss of phosphate from PEP. In the second reaction an unusual cobalt-requiring enzyme effects ring closure with dehydrogenation and loss of the second phosphate. Dehydration in the third step yields dehydroshikimate, which is then reduced by NADPH to shikimate. A three-carbon side chain is then attached via phosphorylation of shikimate and reaction with a second molecule of PEP. Dephosphorylation of this intermediate gives chorismate, the branch point of the pathway. Picture Stats: Views: 308 Filesize: 116.96kB Height: 824 Width: 476 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34815 |