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| Description: Example of reciprocal translocation in Burkitt’s lymphoma. Translocation of the c-MYC gene from chromosome 8 that has lost a portion of its long arm (8q–) to the IgV immunoglobulin gene region on chromosome 14 that has gained a portion from chromosome 8 containing c-MYC (14q+). The translocation overproduces c-MYC protein to cause Burkitt’s lymphomaExample of reciprocal translocation in Burkitt’s lymphoma. Translocation of the c-MYC gene from chromosome 8 that has lost a portion of its long arm (8q–) to the IgV immunoglobulin gene region on chromosome 14 that has gained a portion from chromosome 8 containing c-MYC (14q+). The translocation overproduces c-MYC protein to cause Burkitt’s lymphoma Centromere Reciprocal translocation of chromosomes 8 and 14 —> + c-MYC l9V 8 14 8q— 814q+ Normal Translocation chromosomes rhrnmncnmnc Picture Stats: Views: 69 Filesize: 424.43kB Height: 1718 Width: 2868 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=48431 |