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| Description: Centromere o Transcription of centromeric DNA produces dsRNA W 0.. dsRNA that Is processed by Dicer into siRNA. W e Argonaute joins Chp1 and W other proteins to form the Rfl’S complexthat 0 carriesthesiRNAto the d1romosome, where it binds nascent RNA transaipts from the centromeric repeat sequences. 9 RrTS-siRNA attracts methylases and deacetylases (vai6 and CM) that close chromatin and spread heterochro-
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