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| Description: Effects of acidosis and alkalosis on the oxyhemoglobin dissociation curve. The graph shows the relationship between changes in PO2 (partial pressure of oxygen) and SO2 (saturation of hemoglobin with oxygen). The line in the middle represents the normal hemoglobin saturation with oxygen at various PO2 levels. In acidosis, the curve shifts to the right of normal, so at any given PO2 value, the SO2 is less than normal because of decreased affinity of hemoglobin for oxygen and easier unloading of oxygen to tissues. In alkalosis, the hemoglobin–oxygen curve shifts to the left because of increased affinity of hemoglobin for oxygen, resulting in decreased unloading of oxygen to cells. Three curves are shown, all following the same pattern. They all start at (0, 0), rise sharply, then level off almost horizontally. The lowest curve represents decreased affinity acute acidosis in which p h is low and partial pressure of oxygen is high. This curve passes through about (33, 50). The middle curve represents a normal level. It passes through about (28, 50). The highest curve represents increased affinity acute alkalosis in which p h is high and partial pressure of oxygen is low. This curve passes through about (21, 50). Picture Stats: Views: 27 Filesize: 133.87kB Height: 871 Width: 999 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=49813 |