Author Question: Deficient enzymes that allow various lipids to accumulate in macrophages and monocytes describe: ... (Read 109 times)

armygirl

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Deficient enzymes that allow various lipids to accumulate in macrophages and monocytes describe:
 
  a. Chronic granulomatous disease
  b. Congenital C3 deficiencies
  c. Storage cell diseases
  d. Familial hyperlipidemia disorders

Question 2

A college student seeks medical care for extreme fatigue and swollen lymph nodes in the neck. The WBC count is 11.3  109/L. The differential shows a relative and absolute lymphocytosis.
 
  Many of the lymphocytes are larger than normal, with a basophilic cytoplasm indented by the red blood cells (RBCs). The nuclei are less clumped than normal and some have nucleoli. The rest of the complete blood count (CBC) is normal. What is the most likely diagnosis?
 
  a. Infectious lymphocytosis
  b. Infectious mononucleosis
  c. Lymphoma
  d. Lymphocytic leukemia



joshraies

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Answer to Question 1

ANS: C
Hereditary absence or dysfunction of an enzyme leads monocytes and macrophages to store materials that are not completely degraded. As a group, these are called storage cell diseases.

Answer to Question 2

ANS: B
The description of these cells is that of a reactive lymphocyte. They are a normal response to viral infection. Infectious mononucleosis characteristically shows a lymphocytosis with many reactive T lymphocytes. The age, symptoms, and physical findings also support infectious mononucleosis.



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