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Symptoms of kidney problems include a loss of appetite, back pain (which may be sudden and intense), chills, abdominal pain, fluid retention, nausea, the urge to urinate, vomiting, and fever.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.