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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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When intravenous medications are involved in adverse drug events, their harmful effects may occur more rapidly, and be more severe than errors with oral medications. This is due to the direct administration into the bloodstream.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.