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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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In inpatient settings, adverse drug events account for an estimated one in three of all hospital adverse events. They affect approximately 2 million hospital stays every year, and prolong hospital stays by between one and five days.