Answer to Question 1
Correct Answer: 3
Rationale 1: Anemia and bradycardia are not adverse effects of this drug.
Rationale 2: Hypertension is not an adverse effect of this medication.
Rationale 3: The most common adverse effects of imipramine include dizziness and, to a lesser extent, photosensitivity.
Rationale 4: Polyuria is not an adverse effect of this medication.
Global Rationale: The most common adverse effects of imipramine include dizziness and, to a lesser extent, photosensitivity. Anemia, bradycardia, hypertension, and polyuria are not adverse effects of this drug.
Answer to Question 2
Correct Answer: 4
Rationale 1: Lomefloxacin does not increase the risk of toxicity if taken with lithium.
Rationale 2: Sodium bicarbonate does not increase the risk of toxicity if taken with lithium.
Rationale 3: Calcium iodine does not increase the risk of toxicity if taken with lithium.
Rationale 4: Lithium, when combined with a diuretic such as furosemide, increases the potential for sodium depletion, thereby increasing therapeutic blood levels of lithium to the toxic range.
Global Rationale: Lithium, when combined with a diuretic such as furosemide, increases the potential for sodium depletion, thereby increasing therapeutic blood levels of lithium to the toxic range. Lomefloxacin, sodium bicarbonate, and calcium iodine do not increase the risk of toxicity if taken with lithium.
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