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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.

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The FDA recognizes 118 routes of administration.

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In most climates, 8 to 10 glasses of water per day is recommended for adults. The best indicator for adequate fluid intake is frequent, clear urination.

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Nearly all drugs pass into human breast milk. How often a drug is taken influences the amount of drug that will pass into the milk. Medications taken 30 to 60 minutes before breastfeeding are likely to be at peak blood levels when the baby is nursing.

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Each year in the United States, there are approximately six million pregnancies. This means that at any one time, about 4% of women in the United States are pregnant.

Sequential decline of whale catches in the Antarctic shows the strong effect of human predators. Sequential decline of whale catches in the Antarctic shows the strong effect of human predators.
Beavers can have strong impacts as ecosystem engineers. Beavers can have strong impacts as ecosystem engineers.
Nonverbal communications convey strong, powerful messages that may be negative or positive. Nonverbal communications convey strong, powerful messages that may be negative or positive.
Using a water-based cleaning system helps reduce the hazards from using strong chemicals. Using a water-based cleaning system helps reduce the hazards from using strong chemicals.
How to solve simple percent word problems (Part 1) How to solve simple percent word problems (Part 1)
Percent of oxygen in the atmosphere versus altitude. Percent of oxygen in the atmosphere versus altitude.
Video: Membrane Protein and Facilitated Transport (Passive Vs Active)

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