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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
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Excessive alcohol use costs the country approximately $235 billion every year.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
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Illicit drug use costs the United States approximately $181 billion every year.