The proportion of hemosiderin to ferritin increases when: a. ...

[mrsjacobs44]

The proportion of hemosiderin to ferritin increases when:
 
  a. Iron stores increase.
  b. Anemia is present.
  c. Transferrin increases.
  d. Erythropoietin increases.

Question 2

Which of the following is true for transferrin?
 
  a. It can bind two molecules of ferrous iron.
  b. It binds to a transferrin receptor found on the cell membrane.
  c. It is synthesized in the kidney.
  d. It is normally about 50 saturated with iron.

[recede]

Answer to Question 1

ANS: A
Normally most of the stored iron is in the ferritin or soluble form. However, when iron stores increase, so does the proportion of hemosiderin to ferritin.

Answer to Question 2

ANS: B
Transferrin binds to receptors on the cell membrane, which are called transferrin receptors. Transferrin has two binding sites for ferric (trivalent) iron; it does not bind ferrous iron. It is synthesized in the liver and is normally about one third saturated.