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Approximately 25% of all reported medication errors result from some kind of name confusion.
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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.