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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
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People about to have surgery must tell their health care providers about all supplements they take.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
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Illicit drug use costs the United States approximately $181 billion every year.