The nurse is preparing to administer a prototype drug to a client ...

[Sufayan.ah]

The nurse is preparing to administer a prototype drug to a client with myasthenia gravis. What will the nurse identify as characteristics of this medication?
 
  Standard Text: Select all that apply.
  1. It affects nicotinic acetylcholine synapses in skeletal muscle.
  2. It is the prototype drug.
  3. It does not cross the placenta.
  4. It decreases peristalsis and causes bronchodilation.
  5. It must be used with caution in heart failure.

Question 2

The nurse is concerned that a client receiving pyridostigmine (Mestinon) is experiencing adverse effects. Which assessment findings indicate an adverse effect?
 
  Standard Text: Select all that apply.
  1. Muscle twitching
  2. Nausea
  3. Drooling
  4. Increased peristalsis
  5. Low blood pressure

[shewald78]

Answer to Question 1

Correct Answer: 1,2,5
Rationale 1: Pyridostigmine is used to treat myasthenia gravis and affects the nicotinic acetylcholine synapses in skeletal muscle.
Rationale 2: Pyridostigmine is a prototype drug.
Rationale 3: Pyridostigmine does cross the placenta.
Rationale 4: Pyridostigmine enhances peristalsis and causes bronchoconstriction .
Rationale 5: Pyridostigmine can cause bradycardia and should be used cautiously in clients with heart failure.

Global Rationale: Pyridostigmine is a prototype drugs used to treat myasthenia gravis and affects the nicotinic acetylcholine synapses in skeletal muscle. Pyridostigmine can cause bradycardia and should be used cautiously in clients with heart failure. Pyridostigmine does cross the placenta. Pyridostigmine enhances peristalsis and causes bronchoconstriction .

Answer to Question 2

Correct Answer: 1,2,3
Rationale 1: Muscle twitching is a common adverse effect of pyridostigmine (Mestinon).
Rationale 2: Nausea is a common adverse effect of pyridostigmine (Mestinon).
Rationale 3: Increased salivation is a common adverse effect of pyridostigmine (Mestinon).
Rationale 4: Increased peristalsis is an expected effect of pyridostigmine (Mestinon).
Rationale 5: Hypotension is an expected effect of pyridostigmine (Mestinon).
Global Rationale: Muscle twitching, nausea, and increased salivation are common adverse effecs of pyridostigmine (Mestinon). Increased peristalsis and hypotension are expected effects of pyridostigmine (Mestinon).

[Sufayan.ah]

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[shewald78]

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