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The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
In most climates, 8 to 10 glasses of water per day is recommended for adults. The best indicator for adequate fluid intake is frequent, clear urination.
The average adult has about 21 square feet of skin.
The average human gut is home to perhaps 500 to 1,000 different species of bacteria.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.