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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.