Why are echinocytes seen in PK deficiency? What will be an ...

[imanialler]

Why are echinocytes seen in PK deficiency?
 
  What will be an ideal response?

Question 2

Female heterozygotes for G6PD deficiency have one population of cells that is normal and one that is G6PD deficient because:
 
  a. There is random inactivation of one X chromosome
  b. There is random inactivation of one Y chromosome.
  c. There is random activation of one X chromosome.
  d. There is random activation of one Y chromosome.

[smrerig]

Answer to Question 1

Answer: PK deficiency impairs the production of ADP. This impairment alters the erythrocyte membrane and causes excessive efflux of potassium and influx of calcium and sodium, which dehydrates the RBC, forming spiculed RBCs.

Answer to Question 2

Correct answer: A

[imanialler]

YES! Correct, THANKS for helping me on my review

[yeungji]

Gracias!