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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
Although puberty usually occurs in the early teenage years, the world's youngest parents were two Chinese children who had their first baby when they were 8 and 9 years of age.