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In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
There are approximately 3 million unintended pregnancies in the United States each year.
Approximately one in three babies in the United States is now delivered by cesarean section. The number of cesarean sections in the United States has risen 46% since 1996.
In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
The human body's pharmacokinetics are quite varied. Our hair holds onto drugs longer than our urine, blood, or saliva. For example, alcohol can be detected in the hair for up to 90 days after it was consumed. The same is true for marijuana, cocaine, ecstasy, heroin, methamphetamine, and nicotine.
![When Union troops pushed toward Richmond in June of 1862, these slaves crossed the Rappahannock Rive](https://biology-forums.com/gallery/47/medium_376021_22_08_15_1_40_22_22353567.jpeg)
![The grand opening of the huge Miraflores lock on the Panama Canal in October, 1914. The locks were b](https://biology-forums.com/gallery/47/medium_6_02_03_16_7_45_22_234071402.jpeg)