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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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There are more bacteria in your mouth than there are people in the world.
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Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.