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More than 4.4billion prescriptions were dispensed within the United States in 2016.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.