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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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On average, the stomach produces 2 L of hydrochloric acid per day.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.