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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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The familiar sounds of your heart are made by the heart's valves as they open and close.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.
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Elderly adults are at greatest risk of stroke and myocardial infarction and have the most to gain from prophylaxis. Patients ages 60 to 80 years with blood pressures above 160/90 mm Hg should benefit from antihypertensive treatment.