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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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People about to have surgery must tell their health care providers about all supplements they take.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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There are 20 feet of blood vessels in each square inch of human skin.
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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.