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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.

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Congestive heart failure is a serious disorder that carries a reduced life expectancy. Heart failure is usually a chronic illness, and it may worsen with infection or other physical stressors.

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Oxytocin is recommended only for pregnancies that have a medical reason for inducing labor (such as eclampsia) and is not recommended for elective procedures or for making the birthing process more convenient.

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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.

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Every 10 seconds, a person in the United States goes to the emergency room complaining of head pain. About 1.2 million visits are for acute migraine attacks.

The internal female reproductive organs The internal female reproductive organs
The internal structures of the eye. The internal structures of the eye.
The internal anatomy of the kidney. The internal anatomy of the kidney.
Internal organs of the female reproductive system within the pelvis Internal organs of the female reproductive system within the pelvis
Internal and external forces on the parties Internal and external forces on the parties
Bacteria with Internal Membranes Bacteria with Internal Membranes
Video: Structures that affect circulation - venous return

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