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Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.
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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Normal urine is sterile. It contains fluids, salts, and waste products. It is free of bacteria, viruses, and fungi.