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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.

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The longest a person has survived after a heart transplant is 24 years.

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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.

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Symptoms of kidney problems include a loss of appetite, back pain (which may be sudden and intense), chills, abdominal pain, fluid retention, nausea, the urge to urinate, vomiting, and fever.

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Nearly 31 million adults in America have a total cholesterol level that is more than 240 mg per dL.

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