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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.