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| Description: Endogenous Pathway - 1. Fat & Cholesterol arriving at the Liver or newly synthesised is repackaged into VLDL’s 2. VLDL’s enter the bloodstream between meals & head out to the peripheral tissues 3. VLDL’s meet tissues expressing LPL (muscle & adipose) & release glycerol & fatty acids 4. After the VLDL has lost most of it’s fats it becomes smaller & is known as an IDL 5. Empty HDL is produced as a bi-product – can collect LDL from periphery 6. IDL’s are absorbed from the blood by the liver 7. They are then broken down by Hepatic Lipase intoLDL’s (triglycerides removed) 8. LDL’s have a relatively high cholesterol content with little fatty acids or glycerol 9. LDL circulates & is absorbed by various tissues via binding to LDL receptors 10. Any excess LDL is taken up by the liver via LDL receptors Picture Stats: Views: 12333 Filesize: 929.78kB Height: 1200 Width: 1786 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=12348 |