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| Description: Activin, a member of the TGF? protein family, functions as a morphogen in an animal cap assay by inducing different types of mesoderm at different concentrations. In the absence of activin, no mesodermal derivatives form and the animal caps form cells resembling skin cells. Low concentrations of activin induce mesodermal derivatives resembling blood cells, whereas moderate concentrations induce muscle cells, and higher concentrations induce such mesodermal derivatives as notochord and heart cells.
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