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Description: (a) B-cell receptor and (b) secreted antibody. Immunoglobulins are composed of the two heavy chains and two light chains. Disulphide bonds hold the chains together. Within each immunoglobulin class, the constant regions, including the Fc regions (stems), have identical amino acid sequences. In contrast, the antigen-binding sites formed by the light- and heavy-chain variable regions have unique amino acid sequences and give each antibody its specificity for a particular antigen.
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