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| Description: The replication fork is generated when helicase untwists the DNA to produce two single-stranded template strands. The process of separation of double-stranded DNA to two single strands is called DNA denaturation or DNA melting. Single-strand DNA-binding (SSB) proteins bind to each single-stranded DNA, stabilizing them and preventing them from reforming double-stranded DNA by complementary base pairing.The RNA primer made by DNA primase is at the end of the new strand being synthesized on the bottom template strand. The DNA primase at the fork synthesizes another RNA primer, this one on the top template DNA strand. Each RNA primer is extended by the addition of DNA nucleotides by DNA polymerase III. The polymerases displace bound SSB proteins as they move along the template strands. The new DNAs synthesized are complementary to the template strands. Picture Stats: Views: 1740 Filesize: 448.35kB Height: 796 Width: 768 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=14637 |