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The clonal selection hypothesis

The clonal selection hypothesis
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Description: Each antigen (X or Y) selects a pre-existing clone of specific lymphocytes and stimulates the proliferation and differentiation of that clone.  The diagram shows only B lymphocytes giving rise to antibody-secreting effector cells, but the same principle applies to T lymphocytes.  
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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=1493
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